At least 10-20% of the patients suffering from depression meet criteria for treatment-resistant depression (TRD)...
Our meta-analysis suggests that single administrations ketamine therapy are efficacious in the rapid treatment of unipolar and bipolar depression.
Several studies now provide evidence of ketamine hydrochloride's ability to produce rapid and robust antidepressant effects in patients with mood and anxiety disorders that were previously resistant to treatment.
The clinical use of ketamine infusion therapy for psychiatric disorders and chronic pain management continues to evolve.
Beneficial effects of ketamine in a chronic pain state with allodynia, possibly due to central sensitization
Allodynia is a well-known component of neuropathic pain resulting from injury to the nervous system.
Prolonged Analgesic Effect of Ketamine, anN-Methyl-d-Aspartate Receptor Inhibitor, in Patients with Chronic Pain
We examined the role of N-methyl-D-aspartate (NMDA) receptors in chronic (pathological) pain in humans by using the NMDA receptor antagonist ketamine as a probe.
This study investigated the prevalence of PTSD in Operation Iraqi Freedom/Operation Enduring Freedom (OIF/OEF) service members who were treated for burns in a military treatment center.
Effects of peritraumatic ketamine medication on early and sustained posttraumatic stress symptoms in moderately injured accident victims
The data provide first evidence for a modulating effect of a single-dose ketamine on the severity and duration of posttraumatic stress symptoms in accident victims.
This study provides the first evidence for rapid reduction in symptom severity following ketamine infusion in patients with chronic PTSD.